“We call for the unconditional lifting of the political and economic sanctions, which have crippled our national development,” Mnangagwa told a meeting of the Zanu-PF central committee in downtown Harare.
“We realise that isolation is not splendid or viable as there is more to gain through solidarity, mutually beneficial partnerships.”
The international community will be closely watching the next elections in 2018, which Mnangagwa said would be free and fair and would be held nearer than most people expect.
The vote is due at the end of July in 2018 but there is talk it can be brought forward as early as March.
“Government will do all in its powers to ensure that the elections are credible, free and fair. These elections are nearer than what you expect,” he said without elaborating.